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My laboratory works on genome sequencing, immunoproteogenomics, antibiotics sequencing, and comparative genomics - computational technologies that enabled new applications and allowed scientists to attack biological problems that remained beyond the reach of previous techniques.These genetic variation data provide a deeper understanding of genetic differences among races and individuals, and the detailed data on the association analysis of various diseases greatly promotes the study of population genetics, human disease research, comparative genomics and research in pharmacogenomics.Research Highlights; Bioinformatics and comparative genomics (Xiangchao Gan) Comparative Molecular Genetics of SBP-box Genes (Peter Huijser) Population Genetics (Stefan Laurent) Plant development and diversity (Miltos Tsiantis) Independent Research Group hosted in the Department - Genetic basis for phenotypic evolution (Angela Hay) Past Groups.
This book constitutes the proceedings of the 15th International Workshop Comparative Genomics, RECOMB-CG 2017, held in Barcelona, Spain, in October 2017. The 16 full papers presented were carefully reviewed and selected from 32 submissions. The papers report original research in all areas of Comparative Genomics.
Comparative and Functional Genomics is a new journal in print and electronic formats which contains original research articles and long and short reviews that deal with the post-sequencing phases of genome analysis. The journal will provide a broad forum.
Current DOE Genomics Research. The DOE Genomic Science Program uses microbial and plant genomic data, high-throughput analytical technologies, and modeling and simulation to develop a predictive understanding of biological systems behavior relevant to solving energy and environmental challenges including bioenergy production, environmental remediation, and climate stabilization.
The present article, a primer, explains how one can extract a great deal of information from such analyses that is of great value in our research. The subject of comparative genomics impinges on evolutionary biology and phylogenetic reconstructions of the tree of life, drug discovery programs, function predictions of hypothetical proteins and.
There have been lots of really nice Klebs genomics papers out in the last 18 months or so, examining the evolution of the ST258 clone that carries the KPC gene (K. pneumoniae carbapaenemase) and is wreaking havoc in hospitals all over the place (including recently in Melbourne), and also several hospital-based studies tracking transmission and evolution of local drug-resistant outbreaks.
Read the latest articles of Virus Research at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature. Comparative Genomics and Evolution of Complex Viruses. Edited by Valerian Dolja, Eugene Koonin. Volume 117, Issue 1,. select article Evolutionary genomics of archaeal viruses: Unique viral genomes in the.
Comparative Genomics. Ultimately, human biology must be understood in the context of evolution. Advances in next-generation sequencing technologies have tremendously reduced sequencing costs, which has dramatically expanded the reach of genetic studies to many more non-model organisms.
We know that open access to research is important to authors, their institutions and their funding sources so all papers are freely available online six months after publication. In addition, Genome Research offers an Open Access option in which authors may pay a surcharge to make their paper freely available online immediately upon publication.
Comparative genomics gene regulation enhancer transcription databases This is a preview of subscription content, log in to check access. Springer Nature is developing a new tool to find and evaluate Protocols.
I’m behind in reviewing these papers for you, dear reader, but I hope you’ll click through and take a look at some of these papers if you are interested in the topics. In the following set of papers we have some nice examples of comparative genomics of closely related species and among a clade of species.
A comparative analysis of the genomes of Drosophila melanogaster, Caenorhabditis elegans, and Saccharomyces cerevisiae —and the proteins they are predicted to encode—was undertaken in the context of cellular, developmental, and evolutionary processes. The nonredundant protein sets of flies and worms are similar in size and are only twice that of yeast, but different gene families are.
The progress of genomics research on bamboo is summarized in this review. I focus on development of molecular markers (RAPD, RFLP, AFLP and ISSR) and their application on bamboo studies, including bamboo genes related to flowering, cell wall synthesis.
The annual RECOMB Comparative Genomics Satellite Conference (RECOMB-CG) brings together leading researchers in the mathematical, computational and life sciences to discuss cutting edge research in comparative genomics, with an emphasis on computational approaches and the analysis of novel experimental results.
Comparative genomics, the study of the similarities and differences in structure and function of hereditary information across taxa, uses molecular tools to investigate many notions that long preceded identification of DNA as the hereditary molecule. Vavilov’s ((1922)(1)) law of homologous series.